5th International EDHF Symposium - Endothelium, vasoactive factors and inflammation


Programme

ScientificProgramme(PDF)

Programme Outline

 

Tuesday, June 24

Wednesday, June 25

Thursday, June 26

Friday, June 27

Morning

 

S1
Orchestrated interplay
between endothelium and
vascular smooth muscle

S4
Reactive nitrogen
and oxygen species,
and inflammation

S7
Endothelium and
vascular tone
in the clinic

Afternoon

Satellite symposium A
Renin-angiotensin-
aldosterone system -
Novel treatment options

S2
Ion channels -
Effectors and targets

POSTERS

S5
Young Investigators
Awards Competition

POSTERS

S8
Novel treatment
modalities

Satellite symposium B
We are what we eat-
Diet and the
endothelium

S3
EDHF -
Non-conventional factors
and mechanisms

S6
Focus on the vascular
smooth muscle cell
and matrix

 

Evening

Get together party
Midnight sun lecture

Finnish Evening

Congress Dinner

 

Tuesday, June 24

Satellite symposium A 13.30-15.00: Renin-angiotensin-aldosterone system - Novel treatment options
Chairs: Michel Félétou and Kimmo Kontula

Update of the renin-angiotensin-aldosterone system Frej Fyhrquist
Renin inhibition - a shift in the paradigm? Ilkka Tikkanen
Vascular effects of aldosterone as a treatment target Ole Skott

Coffee and posters


Satellite symposium B 15.30-17.30: We are what we eat - Diet and the endothelium
Sponsored by Valio Ltd
Chairs: Arnold Herman and Heikki Vapaatalo

Nutrition and endothelium Riitta Korpela
Calcium intake and endothelium-mediated vascular tone Ilkka Pörsti
Milk-derived peptides and vascular function Tiina Jauhiainen
Cocoa & chocolate - sin or remedy? Roberto Corti
Protection of endothelial function by grape-derived polyphenols Valérie Schini-Kerth

19 Social programme: Get together party

Midnight sun lecture: EDHF - Yesterday, today, tomorrow Paul M Vanhoutte

Wednesday, June 25

S1 8.30-11.45: Orchestrated interplay between endothelium and vascular smooth muscle
Sponsored by Finnish Cultural Foundation, Pirkanmaa Regional Fund
Chairs: Michael Mulvany and Ilkka Pörsti

Endothelial function and dysfunction from a molecular point of view Ingrid Fleming
Introduction: Paul M Vanhoutte

Coffee and posters

Intercellular communication and the spread of vascular dilatation Chris Garland
Role of smooth muscle cells in coordinating vascular responses Niels-Henrik Holstein-Rathlou
Divergent roles of endothelial NO synthases system in the orchestrated interplay between endothelium and vascular smooth muschle Hiroaki Shimokawa
Role of caveolar compartmentation in EDHF-mediated relaxation: Ca2+ signaling and gap-junctions function are regulated by cav-1 in endothelial cells Chantal Dessy (elevated abstract)
Portal hypertension in rats is associated with blunted EDHF-mediated relaxations in the mesenteric artery: role of ROS and activation of AT1 receptor Stéphanie Ros-Dal (elevated abstract)

Lunch and posters


S2 12.45-14.45: Ion channels - Effectors and targets
Chairs: Chris Garland and Eero Mervaala

Calcium-activated potassium channels and EDHF mediated responses Cor de Wit
TRP channels: Roles in regulation of vascular smooth muscle and endothelial cell function Joseph Brayden
Calcium-sensing receptors in the vasculature Gillian Edwards
EDHF-signalling and arterial blood pressure in mice deficient of endothelial KCa-channels Ralf Köhler (elevated abstract)
Epoxyeicosatrienoic acid-mediated activation of TRPV4 plays a crucial role in flow-induced, EDHF-mediated vasodilatation Annemarieke Loot (elevated abstract)

Coffee and poster walks

S3 15.45-18.00: EDHF - Non-conventional factors and mechanisms
Chairs: William B Campbell and Ilkka Tikkanen

iPLA2beta and Orai1: new determinants of vascular function Victoria Bolotina
C-type natriuretic peptide Heikki Ruskoaho
Adenosine receptor mediated release of factors regulating the neurovascular unit David Harder (elevated abstract)
Effects of caloric restriction on endothelial dysfunction and oxidative stress in diet induced obese C57Bl/6 mice Taru Pilvi (elevated abstract)
Endocannabinoids and vascular control Michael Randall
Tissue engineering of cardiac tissue underpinned by oxidant signaling in the endothelium Greg Dusting (elevated abstract)

19 Social programme: Finnish Evening

Thursday, June 26

S4 8.30-12.00: Reactive nitrogen and oxygen species, and inflammation
Chairs: Valérie Schini-Kerth and Eeva Moilanen

Nitric oxide and mitochondrial interactions in physiology and pathophysiology Salvador Moncada
Introduction: Eeva Moilanen

Coffee and posters

eNOS in physiology and pathophysiology Ulrich Förstermann
Novel aspects of redox signalling in the vascular wall Rhian M Touyz
The relaxing capacity of nitric oxide in mouse aorta smooth muscle cells: role of intracellular calcium Cor Van Hove (elevated abstract)
The human antimicrobial peptide LL-37 induces endothelium- dependent vascular smooth muscle relaxation mediated via the lipoxin A4 receptor ALX Ingrid Berkestedt (elevated abstract)
Post-transcriptional regulation of iNOS expression by dexamethasone and JNK Riku Korhonen (elevated abstract)
Selective depletion of macrophages in atherosclerotic plagues via drug-induced macrophage death Wim Martinet

Lunch and posters


S5 13.00-14.30: Young Investigators Award Competition
Chairs: Paul M Vanhoutte and Mari Hämäläinen
Jury: Paul M Vanhoutte, Salvador Moncada, Arnold Herman, Arthur Weston and Ilkka Pörst
i

Light-induced photorelaxation of coronary arteries: do S-nitrosothiols function as EDHF? Wendy Batenburg
Role of nitric oxide and heme oxygenase-1 in the prevention of intimal hyperplasia development Alessandra Scagliarini
Endothelium-derived hyperpolarizing factor regulates with nitric oxide arterial stiffness during changes in blood flow in humans Jeremy Bellien
Approaches to visualising myoendothelial connections using laser scanning confocal microscopy Claire Hamill
12- and 15-hydroxyeicosatetraenoic acids may function as EDHFs in the human coronary microcirculation Larsen Brandon
Endothelium-dependent contractions in hamster aorta: the essential role of COX-2 and prostaglandin F2α Siu Ling Wong

Coffee and poster walks

S6 15.30-17.30: Focus on the vascular smooth muscle cell and matrix
Chairs: Yuangsheng Gao and Petri Kovanen

Arachidonic acid metabolites as regulators of ionic fluxes in the vascular wall William B Campbell
Deletion of the NO receptor guanylyl cyclase in the mouse Andreas Friebe (elevated abstract)
Preclinical evaluation of new drug-eluting biodegradable poly-D/L-lactic acid vascular stent Ilkka Uurto (elevated abstract)
Glucose as a modulator of connective tissue reorganization by vascular smooth muscle cells Hannu Järveläinen (elevated abstract)
Ion transport systems and vascular remodelling David Beech

19 Social programme: Congress Dinner

Friday, June 27

S7 8.30-9.45: Endothelium and vascular tone in the clinic
Sponsored by the Tampere Tuberculosis Foundation
Chairs: Thomas Lüscher and Mika Kähönen

Measurement of the effects of the endothelium on haemodynamics in humans Stefano Taddei
New insights into the similarities between pulmonary arterial hypertension and cancer...all roads lead to Warburg Stephen Archer
Smoking and genetic variation in nitric oxide synthase gene interact on long-term survival of postmenopausal women following ischemic stroke Pekka Karhunen (elevated abstract)

Coffee and posters


S8 10.15-13.00: Novel treatment modalities
Chairs: Arthur Weston and Heikki Ruskoaho

Future therapeutics: How to influence the endothelium and vascular wall Michel Félétou
Effects of vitamin D and its analogs in vascular function J Ruth Wu-Wong
Cardiovascular effects of simendans Piero Pollesello
Impact of drug-eluting stents on vascular wall Thomas F Lüscher
Endothelium and inflammation - A window of opportunity for PPAR agonists Bart Staels

Lunch

The organizers reserve the right to make any alterations in the programme

Pictures from Tampere
Contact Information      EDHF2008@uta.fi      Fax +358 3 3551 8082      Tel +358 3 3551 4157